A Case of de Novo Interstitial Deletion 16(Q13q22) / 대한주산의학회잡지

Deletion of the long arm of chromosome 16 is uncommon. The causes of deletion are two: one is unbalanced translocation and the other is de novo deletion. In our case, a baby was born with characteristics of the deletion of the long arm of chromosome 16: distinct craniofacial dysmorphism, mild hydrocephalus, ventriculoseptal defect, coarctation of aorta, short neck, low set, small and posterially rotated ears and shortening of long bones. High resolution GTG and RBG banding analyses revealed a karyotype: 46, XY, del(16)(q13q22) de novo.

A Case of Metastatic Malignant Melanoma of the Ovary / 대한산부인과학회잡지

A case of metastatic malignant melanoma of ovary with malignant melanoma of skin is rare. The tumor was discovered 17months following excisional biopsy of left hand for malignant melanoma of the skin. Primary ovarian malignant melanomas are extremely rare and are thought to originate in teratomas. Ovarian melanoma without evidence of residual teratoma must be considered metastatic even in the absence of a previously identifiable cutaneous or mucocutaneous lesion. We had experienced a case of metastatic malignant melanoma of ovary and presented with a brief review of literature.